Why does alcohol disrupt membranes

Wanderlingh , 1,3 G. D'Angelo, 1 V. Conti Nibali, 1 C. Crupi, 1 S. Rifici, 1 C. Corsaro, 1 and G. An exception is the increased behavioral sensitivity in aging animals, which is not matched by changes in their membranes.

When animals are treated chronically with ethanol, their membranes become stiffer, a response that can be regarded as adaptive. Ethanol may favor the uptake of cholesterol or saturated fatty acids into membranes, thus reducing its own effect. Full text links Read article at publisher's site DOI : References Articles referenced by this article 35 Effects of low concentrations of ethanol on the fluidity of spin-labeled erythrocyte and brain membranes.

Ethanol and the physical properties of brain membranes: fluorescence studies. Effect of small molecules on the dipalmitoyl lecithin liposomal bilayer. Phase transition in lipid bilayer Jain J Membrane Biol The effects of ethanol on the thermotropic properties of dipalmitoylphosphatidylcholine. The effects of drugs on membrane fluidity.

Do general anaesthetics act by competitive binding to specific receptors? Lipid spin labels in biological membranes Griffith Title not supplied Pesce Effect of a local anaesthetic on hydrocarbon chain order in membranes. Membrane-disordering action of ethanol: variation with membrane cholesterol content and depth of the spin label probe.

Show 10 more references 10 of Smart citations by scite. The number of the statements may be higher than the number of citations provided by EuropePMC if one paper cites another multiple times or lower if scite has not yet processed some of the citing articles.

Explore citation contexts and check if this article has been supported or disputed. Ethanol affects fibroblast behavior differentially at low and high doses: A comprehensive, dose-response evaluation. Plasma membrane integrity: implications for health and disease. Similar Articles To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation. Ethanol disrupts the physical structure of cell membranes.

The most fluid membranes, including those that are low in cholesterol, are the most easily disordered by ethanol. Although the membrane-disordering effect is small, there is pharmacological, temporal, and genetic evidence that it is important.

Expert interview on biofilm-developing gram-negative pathogens. Preventing Clostridium difficile infections. Relevant pathogens from A-Z.

Reprocessing of Medical Devices. Basis for good hand hygiene compliance: skincare substances, attitudes and role models.

Universally applicable: disinfection wipes with low alcohol content.